Ectopic biomineralization in kidney stone formers compared to non-stone formers
نویسندگان
چکیده
منابع مشابه
Chronic kidney disease in kidney stone formers.
Recent population studies have found symptomatic kidney stone formers to be at increased risk for chronic kidney disease (CKD). Although kidney stones are not commonly identified as the primary cause of ESRD, they still may be important contributing factors. Paradoxically, CKD can be protective against forming kidney stones because of the substantial reduction in urine calcium excretion. Among ...
متن کاملKidney stone formers have more renal parenchymal crystals than non-stone formers, particularly in the papilla region
BACKGROUND We investigated the renoprotective ability of healthy people against kidney stone formation. To clarify intratubular crystal kinetics and processing in human kidneys, we performed a quantitative and morphological observation of nephrectomized renal parenchyma tissues. METHODS Clinical data and pathological samples from 60 patients who underwent radical nephrectomy for renal cancer ...
متن کاملDo Kidney Stone Formers Have A Kidney Disease?
Nephrolithiasis is a highly prevalent disorder affecting approximately one in eleven people and is associated with multiple complications including hypertension, cardiovascular disease, and chronic kidney disease. Significant epidemiologic associations with chronic kidney disease and ESRD have been noted and are reviewed herein, but debate persists in the literature as to whether kidney stone f...
متن کاملPercutaneous renal biopsy specimens in stone formers.
A series of renal biopsy specimens taken at the time of percutaneous nephrolithotomy were investigated for the presence and location of foci of microcalcification. Calcium was found in 18 of 25 (72%) of biopsy specimens from stone formers and in only seven of 30 (23%) of control biopsy specimens. This may indicate defective intrarenal handling of calcium as plasma calcium concentration was norm...
متن کاملUrine protein markers distinguish stone-forming from non-stone-forming relatives of calcium stone formers.
We have investigated urine protein inhibitors of calcium oxalate crystallization to determine whether variations in these proteins are associated with kidney stone disease and whether protein measurements improve the identification of stone formers compared with conventional risk factors (RF). Using Western blotting, we studied variations in the electrophoretic mobility patterns and relative ab...
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ژورنال
عنوان ژورنال: Translational Andrology and Urology
سال: 2020
ISSN: 2223-4683,2223-4691
DOI: 10.21037/tau-19-927